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Concerning the article in the April 1997 issue of the ARCHIVES¹ regarding Stevens-Johnson syndrome (SJS) induced by methazolamide treatment, I would like to add my own anecdotal report. A 62-year-old Japanese woman who underwent routine cataract surgery was given 1 dose of methazolamide, 50 mg, the morning after surgery to control a postoperative intraocular pressure spike. She denied allergies to any medications and had no history of exposure to methazolamide. She returned in 1 day with her pressure reduced and no further complaint. Approximately 12 hours later, itching and swelling developed, with the beginning of an ecchymotic eruption around her face and trunk. She was originally treated by her family physician for what was a supposed possible allergy to plants from her gardening, despite the fact that there was no history of such an allergy. Her symptoms worsened until a full-blown eruption of vesicles and erosions developed over her face, . . . [Full Text of this Article]