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Varicella-Zoster Virus Retinitis Presenting as an Acute Vitreous Hemorrhage
Arch Ophthalmol. 1998;116:104-105.
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Acquired varicella-zoster virus (VZV) retinitis produces 1 of 2 patterns of retinal involvement, each with its own characteristic clinical features. In the acute retinal necrosis syndrome, affected patients are typically healthy and are initially seen with vitritis, retinal vasculitis, and confluent necrotizing retinitis preferentially affecting the peripheral retina.1 In the progressive outer retinal necrosis syndrome, patients are immunodeficient and have multifocal areas of deep retinal opacification located in the peripheral retina with or without macular involvement. They usually have a clear vitreous, no hemorrhage, and an absence of vascular inflammation.2
We recently treated a patient with the acquired immunodeficiency syndrome (AIDS) who had unilateral sudden visual loss and dense vitreous hemorrhage obscuring most retinal findings. Vitreous biopsy and laboratory analysis using polymerase chain reaction established the diagnosis of VZV retinitis.
Report of a Case
A 28-year-old man with AIDS had a 1-day history of severe visual loss in his left eye. He complained that . . . [Full Text of this Article]
Comment
Reprints: James E. Puklin, MD, Kresge Eye Institute, 4717 St Antoine, Detroit, MI 48201 (e-mail: jpuklin@med.wayne.edu).
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