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Corneal Toxicity of Propamidine
Karla J. Johns, MD;
W. Steven Head;
Denis M. O'Day, MD
Arch Ophthalmol. 1988;106(1):68-69.
Abstract
Two patients with Acanthamoeba keratitis developed a corneal abnormality following prolonged treatment with topical 1% propamidine isethionate. In both instances, withdrawal of drug therapy resulted in a gradual clearing of the keratopathy, with no permanent sequelae. The changes we observed may be confused with those of active Acanthamoeba infection.
Author Affiliations
From the Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, Tenn.
Footnotes
Accepted for publication Sept 17, 1987.
Reprint requests to D-5217 Vanderbilt Medical Center North, Nashville, TN 37232 (Dr Johns).
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