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  Vol. 106 No. 1, January 1988 TABLE OF CONTENTS
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Corneal Toxicity of Propamidine

Karla J. Johns, MD; W. Steven Head; Denis M. O'Day, MD

Arch Ophthalmol. 1988;106(1):68-69.


Abstract

• Two patients with Acanthamoeba keratitis developed a corneal abnormality following prolonged treatment with topical 1% propamidine isethionate. In both instances, withdrawal of drug therapy resulted in a gradual clearing of the keratopathy, with no permanent sequelae. The changes we observed may be confused with those of active Acanthamoeba infection.



Author Affiliations

From the Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, Tenn.


Footnotes

Accepted for publication Sept 17, 1987.

Reprint requests to D-5217 Vanderbilt Medical Center North, Nashville, TN 37232 (Dr Johns).



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