Regional specificity in anatomy at the lamina cribrosa

R. L. Radius

Specimens cut in cross section at the level of the lamina cribrosa in normal primate eyes are examined by light microscopy. The density of structural elements, consisting of crosswise-oriented connective-tissue trabeculae, is examined in different regions of the nerve head. It is noted that nasal more than temporal more than superior or inferior regions of the lamina cross section contain increased connective-tissue elements. This regional variation in nerve head anatomy is contrasted with susceptibility patterns of nerve head tissue to pressure elevation in both experimental and clinical glaucoma.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Time-Dependent Effects of Elevated Intraocular Pressure on Optic Nerve Head Axonal Transport and Cytoskeleton Proteins
Balaratnasingam et al.
IOVS 2008;49:986-999.
ABSTRACT | FULL TEXT  

Three-Dimensional Histomorphometry of the Normal and Early Glaucomatous Monkey Optic Nerve Head: Neural Canal and Subarachnoid Space Architecture
Downs et al.
IOVS 2007;48:3195-3208.
ABSTRACT | FULL TEXT  

Three-Dimensional Reconstruction of Normal and Early Glaucoma Monkey Optic Nerve Head Connective Tissues
Burgoyne et al.
IOVS 2004;45:4388-4399.
ABSTRACT | FULL TEXT  

Chronic Ischemia Induces Regional Axonal Damage in Experimental Primate Optic Neuropathy
Cioffi et al.
Arch Ophthalmol 2004;122:1517-1525.
ABSTRACT | FULL TEXT  

Three dimensional analysis of the lamina cribrosa in glaucoma
Morgan-Davies et al.
Br. J. Ophthalmol. 2004;88:1299-1304.
ABSTRACT | FULL TEXT  

Anatomic Relationship between Lamina Cribrosa, Intraocular Space, and Cerebrospinal Fluid Space
Jonas et al.
IOVS 2003;44:5189-5195.
ABSTRACT | FULL TEXT  

Optic Nerve Damage in Experimental Mouse Ocular Hypertension
Mabuchi et al.
IOVS 2003;44:4321-4330.
ABSTRACT | FULL TEXT  

The Optic Nerve Head as a Biomechanical Structure: Initial Finite Element Modeling
Bellezza et al.
IOVS 2000;41:2991-3000.
ABSTRACT | FULL TEXT