Human biochemical components in retinoschisis and detachment
S. S. Feman, J. S. Andrews, M. James and T. Leonard-Martin
Degenerative retinoschisis and rhegmatogenous retinal detachment are
disorders that originate in the peripheral part of the retina. Both of
these disorders are associated with biochemical processes that result in
the finding of metabolic products within fluid-filled spaces. An attempt at
biochemical differentiation of these two retinal disorders is described.
Cholesterol, phospholipids, and proteins were present in the fluid samples,
but low-density lipoproteins were not found. It is suggested that the
cholesterol-to-phospholipid ratio may reflect the degree of retinal
cellular destruction.
