Fluorescein angiography of the optic disc. A longitudinal follow-up study
E. D. Talusan, B. Schwartz and L. M. Wilcox Jr
A comparison of two or more disc fluorescein angiograms performed on
separate occasions was done on 60 eyes of normal subjects and patients with
ocular hypertension, primary open-angle glaucoma, and low-tension glaucoma.
Clinically stable patients did not show any change in their disc
angiographic filling patterns. Eyes that developed new visual-field defects
with increased disc cupping and pallor correspondingly showed new absolute
filling defects or areas of hypofluorescence. In those with established
field defects, however, further changes in the visual field occurred
without obvious changes in the disc fluorescein filling defect. Surgical
lowering of intraocular pressure with or without decrease in disc cupping
and pallor did not result in visible improvement of the disc angiographic
pattern. Thus, the development of new visual-field defects is associated
with changes of the circulation of the optic disc.
