Two-point fluorophotometry in the evaluation of glaucomatous optic disc
S. Sonty and B. Schwartz
The two-point fluorophotometry technique was used to analyze quantitatively
absolute fluorescein filling defects or hypofluorescent areas in
glaucomatous optic discs. Significant differences were found between
hypofluorescent and normal fluorescent areas. The hypofluorescent areas had
slower and lesser filling of fluorescein and a slower disappearance of
fluorescein compared with normal fluorescent areas. Also, the
hypofluorescent areas showed a slow and persistent accumulation of
fluorescein. Age, blood pressure, ocular pressure, and percent area of
optic disc pallor were significantly correlated with changes in the
circulation in the areas of normal fluorescence and hypofluorescence. This
study suggests a decreased blood flow and a smaller vascular bed together
with narrower vessels and increased permeability of the vessels in the
hypofluorescent areas.
