X-linked recessive retinitis pigmentosa and vitreous fluorophotometry. A study of female heterozygotes

D. K. Gieser, G. A. Fishman and J. Cunha-Vaz

Vitreous fluorophotometry was used to assess the functional integrity of the blood-retinal barrier in four female carriers of X-linked recessive retinitis pigmentosa. Abnormal findings in all four carriers suggest that a defect in the blood-retinal barrier, detectable by vitreous fluorophotometry, is a sensitive means by which carriers can be identified.