 |
|
Ultrastructure of Human Cataract in Retinitis Pigmentosa
Joseph Eshaghian, MD;
Nancy S. Rafferty, PhD;
William Goossens
Arch Ophthalmol. 1980;98(12):2227-2230.
Abstract
• A second ultrastructural study of retinitis pigmentosa cataract showed differences from the previous case with respect to sex, age of cataract onset, age at time of cataract extraction, and mode of inheritance of retinitis pigmentosa. Furthermore, the cataract in the present study was limited clinically and preponderantly ultrastructurally to the posterior subcapsular area, which is typical of the location of cataracts associated with retinitis pigmentosa. The cataract was characterized by severe lens fiber disorganization, resulting in intricately distorted membrane configurations and varying cytoplasmic densities; however, "figure eight" configurations as noted in the other report were not observed. Aberrantly migrated epithelial cells were distributed unevenly in the posterior subcapsular zone. New capsular basement membrane, not mentioned in the other report, was conspicuous in our case. Thus, retinitis pigmentosa cataract may have diverse ultrastructural alterations.
Author Affiliations
From the Department of Ophthalmology, University of Iowa, Iowa City (Dr Eshaghian), and Department of Anatomy, Northwestern University, Chicago (Dr Rafferty and Mr Goossens).
Footnotes
Accepted for publication March 28, 1980.
Read in part at the annual meeting of the Association for Research in Vision and Ophthalmology, Sarasota, Fla, May 3, 1979.
Reprint requests to 6333 Wilshire Blvd, Suite 510, Los Angeles, CA 90048 (Dr Eshaghian).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Outcome of cataract surgery in patients with retinitis pigmentosa
Jackson et al.
Br J Ophthalmol 2001;85:936-938.
ABSTRACT
| FULL TEXT
Ocular changes in heredo-oto-ophthalmo-encephalopathy
Bek
Br J Ophthalmol 2000;84:1298-1302.
ABSTRACT
| FULL TEXT
|
