Corneal ulceration and perforation associated with Sjogren's syndrome
R. R. Pfister and G. E. Murphy
Sterile corneal ulcerations and perforations associated with Sjogren's
syndrome affected 18 eyes in 14 patients. Seven of the 18 eyes were
perforated on presentation. Nine of the 18 eyes had received topical
steroid treatment prior to referral. Two of the eyes had undergone recent
anterior segment surgery and suffered perforated corneas postoperatively
while receiving topical steroid treatment. All 14 patients had successful
management of their corneal ulceration or management of their corneal
ulceration or perforation (reepithelialization of the corneal defect,
restoration or maintenance of the anterior chamber, and stromal scarring
with visual acuity equal to or better than on presentation). Two of the 18
eyes had sterile infiltrated ulcers. We believe that this type of ulcer
responds less predictably to therapy than the noninfiltrated lesions.
