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Clinical Specular MicroscopyII. Qualitative Evaluation of Corneal Endothelial Photomicrographs
Ronald A. Laing, PhD;
Marita M. Sandstrom;
Howard M. Leibowitz, MD
From the Department of Ophthalmology, Boston University School of Medicine.
Arch Ophthalmol. 1979;97(9):1720-1725.
Abstract
The clinical specular microscope shows the morphological appearance of the endothelium in normal and abnormal corneas. This instrument resolves the endothelial mosaic of the normal cornea into a quasiregular pattern of contiguous cells having well-defined cell boundaries. Cell size varies over a wide range in a number of disorders, and endothelial cells may assume shapes that are substantially different from their usual hexagonal appearance. Cell boundaries are dark and most commonly appear as a straight, narrow line. However, other types of cell boundaries, collectively referred to as doubled boundaries, have been encountered. Cell boundaries normally intersect in a manner that results in three angles of intersection, each approximately 60°, but variations from this pattern are seen. A number of noncellular structures also can be seen in the endothelial zone.
Footnotes
Accepted for publication Nov 2, 1978.
Reprint requests to Boston University School of Medicine, 80 E Concord St, Boston, MA 02118 (Dr Laing).
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