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  Vol. 97 No. 5, May 1979 TABLE OF CONTENTS
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Benign Epithelioid Cell Nevi of the Iris

Frederick A. Jakobiec, MD; Lemuel T. Moorman, MD; Ira S. Jones, MD

Arch Ophthalmol. 1979;97(5):917-921.


Abstract

• Two benign acquired melanocytic lesions of the iris stroma had distinctive clinical and pathologic features. One tumor was loculated and polypoid, suggesting ectopic glandular tissue, while the other was a flat tumor with a rich surface capillarity. Both lesions histologically were composed of mononucleated, binucleated, and multinucleated hypopigmented epithelioid and elongated "myoid" cells, widely separated in a finely fibrillar eosinophilic stroma. The ultrastructural features of one case included hyperconvoluted nuclei, conspicuous cytoplasmic filaments and rare, filamentarystriated (leptomeric) structures, scant organelles and inclusions except for numerous mitochondria and glycogen granules, small and infrequent melanosomes, and a fibrillary extracellular matrix focally organized into banded basement membrane material.



Author Affiliations

From the Algernon B. Reese Laboratory of Ophthalmic Pathology, Edward S. Harkness Eye Institute, New York City, and the Department of Ophthalmology, University of Colorado, Denver (Dr Moorman).


Footnotes

Accepted for publication July 3, 1978.

Reprint requests to Edward S. Harkness Eye Institute, Box 57, New York, NY 10032 (Dr Jakobiec).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Leiomyoepithelioma of Iris Pigment Epithelium
Li et al.
Arch Ophthalmol 1987;105:819-824.
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Epithelioid Cell Nevus of the Iris
Shields et al.
Arch Ophthalmol 1985;103:235-237.
ABSTRACT  

Are Most Iris 'Melanomas' Really Nevi? A Clinicopathologic Study of 189 Lesions
Jakobiec and Silbert
Arch Ophthalmol 1981;99:2117-2132.
ABSTRACT  

Adenoma of the Iris Pigment Epithelium
Offret and Saraux
Arch Ophthalmol 1980;98:875-883.
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