 |
|
Russell Bodies in Contact-Lens-Associated Giant Papillary Conjunctivitis
Antonio S. Henriquez, MD;
Mathea R. Allansmith, MD
Arch Ophthalmol. 1979;97(3):473-478.
Abstract
• Biopsy specimens of the upper tarsal conjunctiva in soft contact lens-associated giant papillary conjunctivitis were taken during (1) chronic exacerbation, (2) brief remission, and (3) intentional exacerbation. Inflammatory cells were quantitated and compared with inflammatory cells in normal upper tarsal conjunctivae. Specimens were evaluated by light and electron microscopy. The most remarkable feature was the presence of diamond-shaped Russell bodies in 20% of the plasma cells of the second biopsy specimen. A few round Russell bodies were seen in the first biopsy specimen and none in the third.
We concluded that the brief quiescent phase (second biopsy specimen) was characterized by retention of immunoglobulin to produce Russell bodies, and that the active phases of the disease were marked by migration of mast cells into the epithelium and by the presence of eosinophils and basophils in the substantia propria.
Author Affiliations
From the Department of Ophthalmology, Ciudad Sanitaria "Principes De España," Barcelona, Spain (Dr Henriquez), and the Department of Ophthalmology, Harvard Medical School and the Department of Cornea Research, Eye Research Institute of Retina Foundation, Boston (Dr Allansmith).
Footnotes
Accepted for publication May 30, 1978.
Reprint requests to Eye Research Institute of Retina Foundation, 20 Staniford St, Boston, MA 02114 (Dr Allansmith).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Mast Cell Ultrastructure: Comparison in Contact Lens-Associated Giant Papillary Conjunctivitis and Vernal Conjunctivitis
Henriquez et al.
Arch Ophthalmol 1981;99:1266-1272.
ABSTRACT
|
