X-linked ocular albinism in Blacks. Ocular albinism cum pigmento
F. E. O'Donnell Jr, W. R. Green, J. A. Fleischman and G. W. Hambrick
X-linked ocular albinism can be an unsuspected cause of congenital
nystagmus in blacks. In this study, eight of ten black ocular albinos from
two kindreds had nonalbinotic, moderately pigmented fundi and no
transillumination of the iris. We refer to this paradoxical condition as
"ocular albinism cum pigmento." The only constant ophthalmoscopic feature
was a foveal hypoplasia. Biopsy of clinically normal skin to demonstrate
giant pigment granules is the most accurate means of diagnosis.
