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Michael A. Kass, MD; Bernard Becker, MD

Arch Ophthalmol. 1978;96(6):999-1000.

Abstract
• Forty-three ocular hypertensive and 33 ocular normotensive subjects received two doses of topical 1% epinephrine hydrochloride in one eye. The epinephrine was administered twice, ie, at time "zero" (8 AM) and 12 hours later (at 8 PM). The mean intraocular pressure responses at four hours and at 24 hours (12 hours after the last dose of epinephrine) were significantly correlated, r = 0.59 (P <.001). This suggested that the simpler four-hour test was an equally accurate measure of the ocular responsiveness to topical epinephrine.

Author Affiliations
From the Glaucoma Center, Department of Ophthalmology, Washington University School of Medicine, St Louis.

Footnotes
Accepted for publication Sept 20, 1977.

Reprint requests to the Glaucoma Center, Department of Ophthalmology, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110 (Dr Kass).

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