Intraocular irrigating solutions. A comparative study of BSS Plus and lactated Ringer's solution
H. F. Edelhauser, R. Gonnering and D. L. Van Horn
Isolated human corneas maintained normal corneal thickness and endothelial
ultrastructural integrity throughout a three-to four-hour period of
perfusion of BSS plus to the endothelial surface. By comparison, only one
of six human corneas perfused with lactated Ringer's solution was able to
maintain normal thickness and ultrastructural integrity. The other five
corneas perfused with lactated Ringer's solution showed various degrees of
endothelial cell breakdown and corneal swelling during three hours of
perfusion. The results of these studies suggest that BSS plus is a better
solution for maintenance of human corneal endothelium during long-term
(one- to three-hour) surgical procedures.
