Morphological Appearance of the Healing Corneal Endothelium

doi:10.1001/archopht.1978.03910060415002

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Vol. 96 No. 11, November 1978

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Morphological Appearance of the Healing Corneal Endothelium

Gullapalli N. Rao, MD; Edward L. Shaw, MD; Elizabeth Arthur, PhD; James V. Aquavella, MD

Arch Ophthalmol. 1978;96(11):2027-2030.

Abstract

• We studied endothelial cell patterns in both the centraland the superior regions of the cornea in 43 cases of cataractextraction and intraocular lens implantation. During the earlypostoperative period, the central endothelial cells maintainedtheir preoperative appearance. The endothelium within 3 to 4mm of the superior limbus, however, demonstrated large darkareas where no cell outlines were visible, bounded by largecells.

During the late postoperative period, there was an increasein the size and a reduction in the density of the central endothelialcells. In the periphery the previously acellular areas werepopulated with cells of varying diameter.

These changes are consistent with postoperative spreading andsliding of existing cells to cover the traumatized cell-freeareas. Central endothelial cell density in the early postoperativeperiod does not accurately reflect the actual degree of cellloss.

Author Affiliations

From the Department of Ophthalmology, Park Ridge Hospital, Rochester, NY, (Drs Rao, Aquavella, Arthur, and Shaw), and the Rochester (NY) Eye Bank (Dr Aquavella). Dr Shaw is now with the Department of Ophthalmology, St Luke's Hospital, Phoenix, Ariz.

Footnotes

Accepted for publication March 13, 1978.

Reprint requests to 1160 Chili Ave, Rochester, NY 14624 (DrRao).

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