Inflammatory orbital pseudotumor. A clinicopathologic study
R. M. Chavis, A. Garner and J. E. Wright
Fifty-five patients, suspected on clinical grounds of having an
inflammatory orbital pseudotumor, were studied retrospectively. Clinical
groups based on natural history or response to corticosteroid therapy were
correlated with available histopathological findings. These findings were
interpreted without knowledge of clinical grouping or previous pathology
reports. Although dogmatic statements are not possible, several conclusions
are warranted. (1) Bilaterality was not significantly related to response
to steroids or development of systemic disease. (2) B-scan ultrasonography,
while not diagnostic, provided a worthwhile investigative technique. (3)
Germinal follicles are associated with a good prognosis and indicate a
reactive lesion, while diffusely distributed lymphoblasts are associated
with steroid unresponsiveness and a probable neoplastic lymphoid lesions.
(4) Eosinophils are more common in reactive lesions than in presumed
lymphomas. Other cellular components showed no preferential distribution in
either neoplastic or nonneoplastic groups.
