Ultrastructural abnormalities in a Marfan's syndrome lens
P. N. Farnsworth, P. Burke, M. E. Dotto and A. A. Cinotti
The surface ultrastructure of the posterior of the Marfan's syndrome lens
was studied by scanning electron microscopy. All aspects of the
architecture and construction of the capsule, the zonules and their
insertions, the epithelium, and the lens fibers showed a sharp deviation
from normal. The capsular fibrils were abnormally large and grossly
granular. The zonular fibrils, similar in size and granularity to those of
the capsule, contained numerous large aggregates and showed a lack of
parallel orientation. The epithelial cells displayed a coarser than normal
surface granularity and a lack of regularity of form and orientation. The
cortical and nuclear lens fibers displayed a relatively normal surface
pattern but showed poorly defined borders and interdigitating processes.
