Retrolental fibroplasia: I. Clinical observations
J. T. Flynn, G. E. O'Grady, J. Herrera, B. J. Kushner, S. Cantolino and W. Milam
The changes occurring in retrolental fibroplasia were studied in 97
premature infants with fundus photography and fluorescein angiography. The
macrovascular lesion of proliferative retrolental fibroplasia was
identified as a functioning arteriovenous shunt. The microvascular
abnormalities were capillary tufts, collaterals, capillary-free zones, and
neovascular membranes. Regression was signaled by the ingrowth of
capillaries from the shunt into the avascular retina. Cicatrization was
characterized by persistence of the vascular abnormalities of the
proliferative phase and organization of the avascular retina into a
contracting scar.
Pharmacologic and Genetic Manipulation of MMP-2 and -9 Affects Retinal Neovascularization in Rodent Models of OIR
Barnett et al.
IOVS 2007;48:907-915.
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Retinal haemorrhages in a preterm infant following screening examination for retinopathy of prematurity
Lim et al.
Br. J. Ophthalmol. 2006;90:799-800.
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Near Confluent Laser Photocoagulation for the Treatment of Threshold Retinopathy of Prematurity
Rezai et al.
Arch Ophthalmol 2005;123:621-626.
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Increased Retinal Neovascularization in Fas Ligand-Deficient Mice
Davies et al.
IOVS 2003;44:3202-3210.
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Vascular Endothelial Growth Factor and Hepatocyte Growth Factor Levels Are Differentially Elevated in Patients with Advanced Retinopathy of Prematurity
Lashkari et al.
Am. J. Pathol. 2000;156:1337-1344.
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The Effect of Blood Transfusion Protocol on Retinopathy of Prematurity: A Prospective, Randomized Study
Brooks et al.
Pediatrics 1999;104:514-518.
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Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: Direct correlation with clinical retinopathy of prematurity
Hellstrom et al.
Proc. Natl. Acad. Sci. USA 2001;98:5804-5808.
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