Calmette-Guerin bacillus treatment of experimental conjunctival malignant melanoma

doi:10.1001/archopht.95.12.2214

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Vol. 95 No. 12, December 1977

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Calmette-Guerin bacillus treatment of experimental conjunctival malignant melanoma

J. Rutgard, G. A. Peyman, M. Frenkel and S. Saks

Malignant melanoma of the conjunctival region was induced in the golden Syrian hamster. Inoculation of this lesion with Calmette-Guerin bacillus (BCG), 48 hours after injection of 10(3) tumor cells, either slowed, limited, or completely prevented the growth of the tumor in 56% of the treated eyes. In 98% of the control eyes, malignant melanoma grew rapidly and extensively.

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