Dipivefrin use in patients with intolerance to topically applied epinephrine

M. E. Yablonski, D. H. Shin, A. E. Kolker, M. Kass and B. Becker

Twelve patients who had previously demonstrated an intolerance to topically applied epinephrine received dipivefrin 0.1% in one eye and epinephrine 2% in the other eye. An adverse reaction occurred in only one eye (8%) receiving dipivefrin, but in ten (83%) on epinephrine. Topical dipivefrin 0.1% proved useful for lowering intraocular pressure in patients intolerant to topically applied epinephrine.