Optic disc in glaucoma: Topography and extent of fluorescein filling defects
S. L. Fishbein and B. Schwartz
The topography and extent of localized areas of hypofluorescence or
absolute filling defects of the optic discs of glaucomatous patients
correlated positively with the loss of visual field. Filling defects tended
to cluster at the inferior and superior poles of the optic disc and were
closer to the disc margin than to the center. The location of the defects
corresponded with the expected site of visual field loss. There was a
positive correlation between the percent area of the filling defects and
the degree of visual field loss. These observations support the concept
that fluorescein filling defects of the optic disc in glaucoma represent
areas of ischemia that are highly correlated with loss of visual field.
