Intravitreal amphotericin B treatment of Candida endophthamitis
G. A. Stern, C. L. Fetkenhour and R. B. O'Grady,
A 43-year-old heroin addict with Candida albicans endophthalmitis was
treated with a single 5-mug intravitreal injection of amphotericin B. The
diagnosis was confirmed by smears and cultures of a vitrous aspiration. The
patient's accidental death seven weeks after treatment enabled us to obtain
histopathologic evidence that the infection had been cured and that the
amphotericin B had had no toxic effect on the retina. Intravitral
amphotericin B should be considered an important mode of treatment of
Candida endophthalmitis.
