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  Vol. 94 No. 5, May 1976 TABLE OF CONTENTS
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Effects of Microwave Radiation on the Lens Epithelium in the Rabbit Eye

Claire A. Van Ummersen, PhD; Frances C. Cogan, MD

Arch Ophthalmol. 1976;94(5):828-834.


Abstract

• These experiments were conducted to determine the effect of cataractogenic doses of microwave radiation at 2.45 gigahertz (GHz) on the lens epithelium of the rabbit. One hour before animals were killed, tritiated thymidine was injected into the anterior chamber of both eyes at postirradiation intervals varying from six hours to one month. Epithelial peels were made and autoradiographic techniques used to identify cells manufacturing DNA. Comparison of counts from both experimental and control epithelia revealed two patterns, depending on the presence or absence of vesicle strings. Those lenses without vesicle strings showed an initial pronounced suppression of mitotic activity followed by gradual return to normal levels. Those lenses with strings showed a precipitous rise in DNA synthesis on the fourth to fifth day after irradiation. This increased activity may be the result of lens hydration.



Author Affiliations

From the Biology Department, University of Massachusetts, Harbor Campus, Boston (Dr Van Ummersen).


Footnotes

Submitted for publication June 27, 1975.

Reprint requests to Biology Department, College II, University of Massachusetts, Harbor Campus, Boston, MA 02125 (Dr Van Ummersen).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Human Posterior Subcapsular Cataract: A Gross and Flat Preparation Study
Streeten and Eshaghian
Arch Ophthalmol 1978;96:1653-1658.
ABSTRACT  





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