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Myron Yanoff, MD; Harold G. Scheie, MD; Marian I. Allman, MD

Arch Ophthalmol. 1976;94(11):1933-1936.

Abstract
• Late failure of a filtering cicatrix occurred in a patient who had had surgery to control the glaucoma associated with the iris nevus syndrome (Cogan-Reese). The internal surface of the filtration site, as well as the anterior chamber angle, proved to be lined by corneal endothelium that had laid down a new, thick basement membrane (Descemet). The new endothelium-basement membrane probably obstructed the flow of aqueous into the bleb. Endothelialization of a filtering bleb is not unique to the iris nevus syndrome; other causes are discussed.

Author Affiliations
From the Scheie Eye Institute, University of Pennsylvania School of Medicine and Presbyterian-University of Pennsylvania Medical Center, Philadelphia.

Footnotes
Accepted for publication July 2, 1976.

Reprint requests to Scheie Eye Institute, Myrin Circle, 51 N 39th St, Philadelphia, PA 19104 (Dr Yanoff).

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