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J. Heinz Joist, MD; Philip Lichtenfeld; Alan I. Mandell, MD; Allan E. Kolker, MD

Arch Ophthalmol. 1976;94(11):1893-1895.

Abstract
• Platelet function in vitro and in vivo and certain measurements of blood coagulability and fibrinolysis were examined in 12 patients with low tension glaucoma and the results were compared with those obtained in 12 normal subjects matched for age, race, and sex. The data obtained seem to indicate that patients with low tension glaucoma cannot be readily distinguished from individuals of similar age and sex not afflicted with this disorder by measuring these variables. Thus, a "hypercoagulable state," ie, a thrombotic tendency, does not appear to be of major importance in the pathogenesis of this disorder.

Author Affiliations
From the Departments of Medicine, Pathology, and Ophthalmology (Glaucoma Center) Washington University School of Medicine, St Louis. Dr Mandell is now with the Department of Ophthalmology, University of Tennessee, College of Medicine, Memphis.

Footnotes
Accepted for publication April 9, 1976.

Reprint requests to Hemostasis and Thrombosis Laboratory, Division of Laboratory Medicine, Washington University School of Medicine, Barnes Hospital, St Louis, MO 63110 (Dr Joist).

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