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A Case Report

Joseph B. Michelson, MD; Norman T. Felberg, PhD; Jerry A. Shields, MD; Leonard Foster

Arch Ophthalmol. 1975;93(9):794-796.

Abstract
Plasma carcinoembryonic antigen (CEA) levels were found to be elevated in a 62-year-old woman who came to us with a diffuse choroidal mass in the left eye. Although a metastatic tumor was suspected clinically, a thorough medical evaluation failed to detect a primary lesion and the eye was enucleated. The histologic diagnosis was metastatic adenocarcinoma. On immunohistologic assay, the choroidal metastases stained positively for CEA. We believe this to be the first CEA-positive intraocular tumor to be reported.

Author Affiliations
From the Department of Molecular Biology of the Research Institute (Drs. Michelson and Felberg and Mr. Foster) and the Oncology Unit of the Retina Service (Dr. Shields), Wills Eye Hospital and Research Institute, Philadelphia.

Footnotes
Submitted for publication June 5, 1974.

Reprint requests to 1601 Spring Garden St, Philadelphia, PA 19130 (Dr. Michelson).

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