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IV. Immunity in Owl Monkeys to Reinfection With Trachoma

C.E. Ovid Fraser, PhD; Dorothy E. McComb; Edward S. Murray, MD; A. Bruce MacDonald, PhD

Arch Ophthalmol. 1975;93(7):518-521.

Abstract
In a study of trachoma in owl monkeys, it was found that owl monkeys are equally susceptible to low and high doses of trachoma and that resistance to reinfection persisted for six months in the majority of animals. Previous infections with a single trachoma type did not elicit greater resistance than previous infections with two types.

Both serum antibodies and eye secretion titers correlated well with resistance to reinfection, but it is not as yet clear if either or both play a substantial role in immunity to trachoma.

Author Affiliations
From the New England Regional Primate Research Center, Southborough, Mass, and the Department of Microbiology, Harvard University School of Public Health, Boston.

Footnotes
Submitted for publication May 14, 1974.

Reprint requests to New England Regional Primate Research Center, 1 Pine Hill Dr, Southborough, MA 01772 (Dr. Fraser).

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