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Dose-Response Study

Laurence S. Harris, MD; Yaffa Kahanowicz, MD

Arch Ophthalmol. 1975;93(7):501-503.

Abstract
An experimental rabbit uveitis model was used to establish a dose response range for topical administration of fenoprofen (dl-2-(3-phenoxyphenyl) propionic acid. The 0.3% concentrate group was not distinguishable from the untreated group, and 3% concentrate proved highly irritating. Fenoprofen 1%, pH 6.4, proved most efficacious and had an effect comparable to dexamethasone phosphate 0.1%, seen in a previous study.

Author Affiliations
From New York Hospital, Society of the New York Hospital, New York.

Footnotes
Submitted for publication March 4, 1974.

Reprint requests to 525 E 68th St, New York, NY 10021 (Dr. Harris).

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