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III. Experiments in Vivo

Felipe Huamonte, MD; Miguel F. Refojo, DSc; Antonio Banuelos, MD

Arch Ophthalmol. 1975;93(5):354-356.

Abstract
Experimental scleral buckling was obtained in rabbits by using expandable silicone rubber implants under scleral trap doors. Buckle heights ranged from 2.3 to 4 mm after injection of 0.05 to 0.15 ml of fluid into the implants. The rate of decrease in buckle height followed up ophthalmoscopically for five months, was found to be slow and continuous and was caused mainly by loosening of the scleral flaps rather than by the diffusion of fluid from the implants. Implants expanded with chloramphenicol solutions provided sustained release of the antibiotic in the area of the operation. This was confirmed in agar plates by inhibition of the growth of Sarcina lutea around subimplant tissues and the expanded implants that were recovered post mortem. These implants provide an opportunity to modify the buckle height easily, either during the procedure or postoperatively.

Author Affiliations
From the Retina Foundation, Boston. Dr. Huamonte is now with the University of Illinois Eye and Ear Infirmary, Chicago.

Footnotes
Submitted for publication July 20, 1973.

Reprint requests to 20 Staniford St, Boston, MA 02114 (Dr. Refojo).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Expandable Silicone Implants for Scleral Buckling: IV. Experiments With An Explant for Macular Breaks
Huamonte et al.
Arch Ophthalmol 1975;93:429-431.
ABSTRACT