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Robert A. Ralph, MD; Marshall G. Doane, PhD; Claes H. Dohlman, MD

Arch Ophthalmol. 1975;93(10):1039-1043.

Abstract
• The continuous delivery of fluids to the ocular surfaces of 12 patients, for a collective total of 1,500 days, was achieved by means of a mobile perfusion pump. One patient used this device intermittently for a total of 2 years. Severe dry-eye symptoms were ameliorated in each patient by the constant perfusion. In various situations, the following perfusion fluids have been tried: commercial balanced salt solution, commercial artificial tear solutions, acetylcysteine, and autologous and homologous serum and plasma. In spite of disadvantages related to its size and weight, the pump seems to be of considerable value, especially following severe chemical burns and after keratoplasty or reconstruction of the lids and fornices in the severely dry eye.

Author Affiliations
From the Cornea Service, Massachusetts Eye and Ear Infirmary, and the Department of Cornea Research, Retina Foundation, Boston.

Footnotes
Submitted for publication May 21, 1974.

Reprint requests to Department of Ophthalmology, Georgetown University Medical Center, 3800 Reservoir Rd NW, Washington, DC 20007 (Dr. Ralph).

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