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David G. Cogan, MD

Arch Ophthalmol. 1975;93(1):1-8.

Abstract
Seven cases illustrate the ocular pathology of disseminated intravascular coagulopathy in its several stages, and correlate these changes with the clinical manifestations. The prime abnormalities consisted of detachments of the retina, vacuolar disruption of the pigment epithelium, choroidal hemorrhage, and, most importantly, thrombotic occlusion of the choriocapillaris and of the juxtaposed vessels in the submacular and peripapillary regions. The changes were characteristically symmetrical in the two eyes.

Author Affiliations
From the Howe Laboratory of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston; and the Clinical Branch, National Eye Institute, Bethesda, Md.

Footnotes
Submitted for publication Aug 20, 1974.

Presented as the 11th Annual Edwin B. Dunphy Lecture, Boston, May 18, 1974.

Reprint requests to National Eye Institute, Bldg 10, Room 10N313, 9000 Rockville Pike, Bethesda, MD 20014 (Dr. Cogan).

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