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Effect of Surgical Opening of the Anterior Chamber in the Normal Eye

Richard F. Brubaker, MD; Fenwick C. Riley, Jr., MD

Arch Ophthalmol. 1972;87(4):438-442.

Abstract
The anterior chamber of one eye of anesthetized rabbits was surgically opened, simulating the condition which exists prior to cataract extraction in man. Compared to the control eye, the weight of the lens and vitreous was found to diminish at an average rate of 5 mg/min. If it is assumed that the observed weight loss is due to loss of vitreous water, the volume of the vitreous compartment will have diminished by 50µl ten minutes after opening the anterior chamber. This volume is comparable to that lost from the vitreous body as a result of preoperative administration of hyperosmotic agents. It is speculated that the fluid loss from the vitreous body resulting from opening the anterior chamber will not be affected by preoperative maneuvers used to reduce the volume of the vitreous compartment.

Author Affiliations
Rochester, Minn

From the Department of Ophthalmology, Mayo Clinic, Rochester, Minn.

Footnotes
Submitted for publication Sept 27, 1971.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, Minn 55901 (Dr. Brubaker).

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