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Richard W. Darrell, MD

Arch Ophthalmol. 1972;87(4):411-416.

Abstract
Corneal stroma previously damaged by herpes simplex virus (HSV) did not yield virus or cause seroconversion when transplanted into normal rabbit eyes. After penetrating keratoplasty, the recipient rabbits were observed for up to 15 months for evidence of keratitis, virus shedding, or seroconversion. Although five episodes of corneal ulceration occurred, two of them in contralateral ungrafted eyes, HSV was not recovered on culture, and seroconversion did not occur, even following challenge with corticosteroids and ultraviolet irradiation.

Author Affiliations
New York

From the Department of Ophthalmology, Columbia University, and the Edward S. Harkness Eye Institute, New York.

Footnotes
Submitted for publication Aug 4, 1971.

Reprint requests to Edward S. Harkness Institute, 635 W 165th St, New York 10032 (Dr. Darrell).

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Arch Ophthalmol 1972;88:412-417.
ABSTRACT