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III. Recurrent Inflammation Stimulated by Systemic Administration of Antilymphocyte Serum and Normal Horse Serum

Robert A. Nozik, MD; G. Richard O'Connor, MD

Arch Ophthalmol. 1971;85(6):718-722.

Abstract
Rabbits with inactive retinochoroiditic scars due to experimental toxoplasmosis were subjected to a series of intravenous inoculations of antilymphocyte serum. Two out of five rabbits so treated developed reactivation of their retinochoroiditic lesions. All of a similar group of rabbits treated with intravenous inoculations of normal horse serum developed reactivations of their lesions. Some mechanisms considered responsible for the breakdown of these healed lesions are discussed.

Author Affiliations
San Francisco

From the Francis I. Proctor Foundation for Research in Ophthalmology, and the Department of Ophthalmology, University of California, San Francisco.

Footnotes
Submitted for publication Nov 4, 1970.

Reprint requests to Francis I. Proctor Foundation, University of California, San Francisco Medical Center, San Francisco 94122 (Dr. Nozik).

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