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II. Attempts to Stimulate Recurrences by Local Trauma, Epinephrine, and Corticosteroids

Robert A. Nozik, MD; G. Richard O'Connor, MD

Arch Ophthalmol. 1970;84(6):788-791.

Abstract
Attempts to reactivate healed, experimentally induced toxoplasmic retinochoroiditis in the rabbit were unsuccessful. Three possible causes of recurrence of human toxoplasmic lesions were evaluated: blunt local trauma, systemically administered epinephrine, and systemically administered corticosteroids. In no case could reactivation be observed ophthalmoscopically. However, minimal round cell infiltration was seen in histologic preparations from the eyes of hydrocortisone-treated animals.

Author Affiliations
San Francisco

From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California Medical Center, San Francisco.

Footnotes
Submitted for publication June 8, 1970.

Reprint requests to Francis I. Proctor Foundation, University of California Medical Center, San Francisco 94122 (Dr. Nozik).

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