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Distensibility of the Intraocular Vascular Bed
Milton Best, MD;
Michael Blumenthal, MD;
Miles A. Galin, MD
Arch Ophthalmol. 1970;84(5):630-634.
Abstract
By direct ophthalmic artery perfusion studies in enucleated cat eyes, volume changes in the intraocular vascular bed were determined after alterations in ophthalmic artery perfusion pressure. Vascular distensibility curves obtained in this manner indicate that the resistance to distension of the intraocular vascular bed increases as its volume increases. A semilogarithmic relationship exists between volume changes in the intraocular vascular bed and alterations of perfusion pressure in the ophthalmic artery. The slope of this relationship, termed the "coefficient of vascular rigidity," is constant at intraocular pressures between 10 and 40 mm Hg. Levarterenol (Levophed) bitartrate does not measurably affect vascular distensibility as measured in this study.
Author Affiliations
New York; Jerusalem, Israel; New York
From the Department of Ophthalmology, New York Medical College, New York (Drs. Best and Galin), and the Department of Ophthalmology, Hadassah Medical School, Jerusalem, Israel (Dr. Blumenthal).
Footnotes
Submitted for publication Feb 13, 1970.
Reprint requests to New York Medical College, Center for Chronic Disease, Bird S. Coler Hospital, New York 10017 (Dr. Best).
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