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  Vol. 84 No. 5, November 1970 TABLE OF CONTENTS
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Dose Response Analysis of Pilocarpine-Induced Ocular Hypotension

Laurence S. Harris, MD; Miles A. Galin, MD

Arch Ophthalmol. 1970;84(5):605-608.


Abstract

Single dose loading with pilocarpine hydrochloride concentrations from 1% to 10% was performed in a series of open-angle glaucomatous patients. No significant differences in the ocular hypotensive response occurred at any dose level. On chronic administration, however, 4% pilocarpine produced a significant improvement over the 1% solution in both intraocular pressure and outflow facility. An increase in concentration to 8% produced no additional change in either factor.



Author Affiliations

New York

From the Department of Ophthalmology, New York Medical College, New York.


Footnotes

Submitted for publication April 3, 1970.

Reprint requests to Department of Ophthalmology, New York Medical College, 1249 Fifth Ave, New York 10029 (Dr. Harris).



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