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Michael Kaczurowski, MD

Arch Ophthalmol. 1970;84(3):316-320.

Abstract
An inbred line of Japanese mice established in 1957 and named the "KK Strain" has been studied for many attributes of its congenital diabetes. This study documents the occurrence of angiopathy in the retinal vessels and contrasts these findings to a similar sized and aged control group of nondiabetic Swiss Webster mice. Studies were made on flat retinal preparations following intracardiac injection of 4% silver nitrate and 3% thiodiglycol in water. Vascular constrictions, dilations, microaneurysms, mural thickening, and proliferation of connective tissue were shown in increasing incidents in the KK mice as they became older.

Author Affiliations
Philadelphia

From the Wills Eye Hospital and Research Institute, Philadelphia.

Footnotes
Submitted for publication Sept 11, 1969.

Reprint requests to Wills Eye Hospital and Research Institute, 1601 Spring Garden St, Philadelphia 19130 (Dr. Kaczurowski).

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