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II. Behavioral Studies in Strabismic Amblyopia

Gunter K. von Noorden, MD; John E. Dowling, PhD

Arch Ophthalmol. 1970;84(2):215-220.

Abstract
Esotropia was experimentally produced in three and exotropia in two rhesus macaque monkeys at different ages after birth. The animals were conditioned to respond behaviorally to Landolt rings of different sizes in order to determine visual acuity. After this task was mastered by the animals, complete tarsorrhaphy was performed on the fixating eye, and acuity measurements were resumed with the deviated eye. Strabismic amblyopia was present in two esotropic monkeys that had experimental onset of strabismus during the first week of life. In both animals the amblyopic eye showed recovery in acuity but had not reached the level of acuity of the sound eye by the time this report was written. Amblyopia was absent in the third esotropic animal, whose onset of surgical strabismus was at 15 months, and it was absent in the two exotropic monkeys, who could hold fixation with either eye.

Author Affiliations
Baltimore

From the Wilmer Institute of Ophthalmology, the Johns Hopkins University School of Medicine and Hospital, Baltimore.

Footnotes
Submitted for publication Dec 30, 1969.

Reprint requests to the Wilmer Institute, the Johns Hopkins Hospital, 601 N Broadway, Baltimore 21205 (Dr. von Noorden).

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