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Harvey H. Slansky, MD; Daniel W. Tolpin, MD; Robert G. Webster, Jr., MD

Arch Ophthalmol. 1970;83(6):760-764.

Abstract
Collagenase was demonstrated in the epithelium in eight of ten corneal explants of thyroxineinduced metamorphosing tadpoles. There was no detection of collagenase in explants of "resting" control tadpoles, or in explants denuded of their epithelium in the metamorphosing series. The implications of such an enzyme in the morphological changes occurring in the cornea which accompany metamorphosis are discussed.

Author Affiliations
Boston

From the Department of Cornea Research, Retina Foundation, Boston.

Footnotes
Submitted for publication Nov 6, 1969.

Reprint requests to the Department of Cornea Research, Retina Foundation, 20 Staniford St, Boston 02114 (Dr. Slansky).

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ABSTRACT