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Potentiation With Normal Horse Serum and Antilymphocyte Serum

Gilbert Smolin, MD; Masao Okumoto, MA

Arch Ophthalmol. 1970;83(6):746-751.

Abstract
Twenty-five rabbits were treated with systemic doses of antilymphocyte serum (ALS) or normal horse serum (NHS) prior to the inoculation of the cornea with herpes simplex virus (PH strain). The severity of the clinical response to the virus was enhanced by ALS and even more so by NHS. The possible mechanism responsible for this potentiation were examined. A better model for the production of severe herpes simplex keratitis was established.

Author Affiliations
San Francisco

Footnotes
Submitted for publication Oct 3, 1969.

Reprint requests to the Francis I. Proctor Foundation, University of California, San Francisco Medical Center, San Francisco 94122 (Dr. Smolin).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Suppression of Corneal Graft Reaction by Antilymphocyte Serum: III. Effect of Pretreatment of Donor Animals
Smolin and Hyndiuk
Arch Ophthalmol 1971;85:451-454.
ABSTRACT