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III. Experimental Degeneration of the Rabbit Retina Induced by Hemoglobin Injection Into the Vitreous

Arch Ophthalmol. 1970;83(4):470-474.

Abstract
Early degeneration of the rabbit retina after hemoglobin injection into the vitreous was studied by light and electron microscopy. Structural changes including a pyknotic change in rod nuclei and early rod degeneration were apparent three days after injection. Electron-dense bodies began to appear within the degenerating pigment epithelium cells on the seventh day. These bodies may be degenerating products of outer rod segments.

Footnotes
Submitted for publication Jan 22, 1969.

From the Department of Retina Research, Retina Foundation, Boston, and the Foundation of Medical Research, Paris. Dr. Regnault is a senior research fellow under the Fulbright-Hays program.

Reprint requests to Library, Retina Foundation, 100 Charles River Plaza, Boston 02114.

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