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II. Hemoglobin Degradation

Arch Ophthalmol. 1970;83(4):466-469.

Abstract
Using isotopes, this study traced hemoglobin breakdown products after hemoglobin injection into rabbit vitreous. Elimination of breakdown products was rapid during the first week, and after one month only 10% of the initial radioactivity was detected. Chromatography strongly suggests that a bilirubin-like product is present 18 days after injection.

Footnotes
Submitted for publication Jan 22, 1969.

From the Department of Retina Research, Retina Foundation, Boston, and the Foundation of Medical Research, Paris. Dr. Regnault is a senior research fellow under the Fulbright-Hays porgram.

Reprint requests to Library, Retina Foundation, 100 Charles River Plaza, Boston 02114.

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