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Chronic Fluoride Ingestion in RabbitsAbsence of Ocular Effects
Michael A. Bloome, MD;
Hermann M. Burian, MD
Arch Ophthalmol. 1970;83(3):354-356.
Abstract
Twenty rabbits received large doses of orally administered fluoride for 3 to 5 months. Baseline and subsequent electroretinogram (ERG) and ophthalmoscopic examinations were done on each rabbit as well as on a group of control rabbits. Although bone concentrations of fluoride were compatible with chronic system fluorosis, there were no significant differences in the ERGs, fundi, or microscopic sections of the treated eyes as compared to the control eyes.
Author Affiliations
Iowa City
From the ERG Laboratory of the Department of Ophthalmology, and the Neurosensory Center, College of Medicine, University of Iowa, Iowa City.
Footnotes
Submitted for publication Aug 20, 1969.
Reprint requests to Department of Ophthalmology, University Hospitals, Iowa City 52240 (Dr. Bloome).
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