This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (65)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Douglas R. Anderson, MD; William H. Spencer, MD

Arch Ophthalmol. 1970;83(3):324-335.

Abstract
Colloidal iron stains showed that many optic nerve gliomas contain mucoid material. This material is extracellular, as demonstrated especially by electron microscopy of two gliomas. In one glioma it was particularly abundant and it apparently contributed to a sudden increase of proptosis due to rapid enlargement of the tumor. There was no evidence of necrosis or degeneration in these tumors, by light or by electron microscopy, and the accumulation of mucosubstance is not considered to be a degenerative change. The tumor cells were mainly astrocytes. These had certain embryonic ultrastructural features, but did not exhibit malignant alteration.

Author Affiliations
San Francisco

From the University of California Eye Pathology Laboratory and the Francis I. Proctor Foundation for Research in Ophthalmology, University of California Medical Center, San Francisco. Dr. Anderson is now at Bascom Palmer Eye Institute, Miami, Fla.

Footnotes
Submitted for publication May 6, 1969.

Read before the spring meeting of the Association for Research in Ophthalmology, Sarasota, Fla, April 21, 1969.

Reprint requests to Bascom Palmer Eye Institute, PO Box 875, Biscayne Annex, Miami, Fla 33152 (Dr. Anderson).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Pilocytic astrocytomas as hamartomas: implications for treatment
Parsa and Givrad
Br J Ophthalmol 2008;92:3-6.
FULL TEXT  

Juvenile pilocytic astrocytomas do not undergo spontaneous malignant transformation: grounds for designation as hamartomas
Parsa and Givrad
Br J Ophthalmol 2008;92:40-46.
ABSTRACT | FULL TEXT  

Orbital Optic Nerve Glioma in Adult Life
Wulc et al.
Arch Ophthalmol 1989;107:1013-1016.
ABSTRACT  

Chiasmatic and Hypothalamic Extension of Optic Nerve Glioma
McDonnell and Miller
Arch Ophthalmol 1983;101:1412-1415.
ABSTRACT  

The Architecture of Optic Nerve Gliomas With and Without Neurofibromatosis
Stern et al.
Arch Ophthalmol 1980;98:505-511.
ABSTRACT  

Large Optic Nerve Glioma With Normal Vision
Goodman et al.
Arch Ophthalmol 1975;93:991-995.
ABSTRACT  

The Orbit
Trokel
Arch Ophthalmol 1971;86:583-594.
 

The Retina and Optic Nerve
L'Esperance
Arch Ophthalmol 1971;86:210-232.
 

Visual Morbidity With Chiasmal Glioma: Long-Term Studies of Visual Fields in Untreated and Irradiated Cases
Glaser et al.
Arch Ophthalmol 1971;85:3-12.
ABSTRACT  

Neuro-ophthalmology
Knox
Arch Ophthalmol 1971;85:111-126.