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The Isolation of Herpesvirus in an Iris Organ Culture System

David N. Tucker, MD; Albert Z. Kapikian, MD

Arch Ophthalmol. 1969;82(6):827-829.

Abstract
Experimental herpes simplex uveitis was induced in rabbits within three days following anterior chamber inoculation of herpes simplex virus. The reisolation of this virus from aqueous humor specimens of these animals was achieved in both rabbit iris organ cultures and WI38 cell cultures. The sensitivity of virus recovery in both these virologic systems was compared.

Author Affiliations
Bethesda, Md

From the Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, Md. Dr. Tucker is now at the Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Fla.

Footnotes
Submitted for publication June 30, 1969.

Reprint requests to Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Bethesda, Md (Dr. Kapikian).

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