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Steven Yeh, MD; Colleen M. Cebulla, MD, PhD; S. Robert Witherspoon, MD; Geoffrey G. Emerson, MD, PhD; M. Vaughn Emerson, MD; Eric B. Suhler, MD, MPH; Thomas A. Albini, MD; Christina J. Flaxel, MD

Arch Ophthalmol. 2009;127(9):1218-1221.

Three patients with chronic, noninfectious uveitis requiring immunosuppressive therapy underwent fluocinolone acetonide (FA) implant exchange complicated by dissociation of the medication reservoir from its anchoring strut. In 2 patients, the medication reservoir descended into the vitreous cavity and required pars plana vitrectomy with intraocular foreign body removal techniques for its retrieval. The use of viscoelastic or perfluorocarbon to elevate the device was helpful in the safe removal of the FA implant device. Surgeons performing FA implant exchange should be aware of this potential complication and anticipate the possible need for vitreoretinal instrumentation and personnel. Patients undergoing FA explantation or exchange should be counseled regarding this potential complication prior to surgery.

Author Affiliations: Department of Ophthalmology, Casey Eye Institute (Drs Yeh, Witherspoon, G. G. Emerson, M. V. Emerson, Suhler, and Flaxel) and Ophthalmology Service, Portland Veterans Affairs Medical Center (Dr Suhler), Portland, Oregon; and Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida (Drs Cebulla and Albini).

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