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Lawrence W. Hirst, MD, MPH; Roy A. Axelsen, BSc, MD, FRCPA; Ivan Schwab, MD

Arch Ophthalmol. 2009;127(1):31-32.

Objective  To measure the rate of histopathologically identified ocular surface squamous neoplasia (OSSN) in pterygium specimens.

Methods  All pterygium specimens collected from consecutive patients between April 8, 2003, and February 6, 2008, were submitted for histopathologic examination, and the rate of OSSN was calculated.

Results  The rate of OSSN was 9.8% (52 of 533) insequential pterygium specimens.

Conclusions  This rate of unsuspected OSSN suggests that all specimens of pterygium should be submitted for histopathologic examination and that patients in whom OSSN is noted should be examined at more frequent intervals so any clinical OSSN that develops can be identified at an early stage.

Author Affiliations: Queensland Eye Institute and Princess Alexandra Hospital, University of Queensland (Drs Hirst and Schwab); IQ Pathology (Dr Axelsen), Brisbane, Australia; and University of California, Davis (Dr Schwab).

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